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We terminated coupled respiration by the addition of the ATP synthase inhibitor oligomycin (2.0 μM) where ATP recycling cannot contribute and there is a stable decrease in OCR.
A stable decrease in ROCK1 expression was observed in HaCaT-ROCK1-KD cells, compared to HaCaT-NSC and HaCaT-ROCK2-KD cells (Figure 1A, B).
We have also evaluated complex I activity, and, as previously characterized by our group (16, 17), sPD cybrid cell lines show a stable decrease in this mitochondrial activity (Fig. 1C).
Moreover, recent studies have demonstrated that it can promote a stable decrease in blood pressure, improve clinical symptoms, regulate the rennin angiotensin system, improve insulin resistance and salt sensitivity, and decrease serum levels of total cholesterol, triglycerides, and low-density lipoprotein cholesterol [ 15, 46, 47].
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We show that these vectors induced a strong, stable decrease in endogenous GFAP and vimentin expression in primary cultured astrocytes.
Contrastingly, the present study demonstrated a gradual and stable decrease in serum OC levels in rabbits from month 5 to month 11, thereafter, similar to CTX-II levels.
We are witnessing a continuous and stable decrease in the number of children placed in residential institutions, and an evident increase in the number of children in day-care centres in local communities and in foster families.
In Wagner et al. 1991 [ 17] detomidine 0.02 mg/kg given intravenously resulted in a significant but stable decrease in cardiac output and respiratory rate compared to unsedated horses between 15 and 60 minutes after administration.
Moreover very low caloric diets (<800 Kcal) are associated with substantial nutritional deficiencies, lean mass loss, greater weight regain secondary to stable decrease in energy expenditure and increased risk of gallstones and cholecystitis due to increased peripheral mobilization of cholesterol.
This absence of a stable rate decrease reflects a decrease in TB CNRs among middle-age persons, primarily women, which is compensated for by an increase in CNRs in young adults, primarily men (10 ).
A significant and stable decrease (9%, p < 0.05) in 24 h albuminuria was demonstrated with time.
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