The phrase "a split trial" is correct and usable in written English.
It can be used in legal contexts to refer to a trial that is divided into separate phases or parts, often to address different issues or aspects of a case.
Example: "The court decided to conduct a split trial, first addressing liability and then moving on to damages."
Alternatives: "divided trial" or "segmented trial".
However, a recent large prospective randomized trial (Split Trial) reported no difference in AKI incidence in patients receiving either balanced crystalloids or isotonic salt solutions [31].
However, a recent large prospective randomized trial (Split Trial) reported no difference in AKI incidence in patients receiving either balanced crystalloids or isotonic salt solutions [ 31].
Similarly, the recent SPLIT trial also failed to demonstrate a significant difference between saline and a balanced solution (Plasma-Lyte) in critically ill patients [26], although this study has been subject to a lot of criticisms [21].
Infection index was compared in the greenhouse in a split plot trial with five isolates applied to soil, seed, or both arranged in a randomized complete block design with four replications.
Pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST) were used to determine strain specific infection dynamics in treated and control groups in a split herd trial conducted on 2 commercial dairy farms.
These findings were not confirmed by the randomized SPLIT trial [16].
On the contrary, the SPLIT trial (comparing saline vs balanced crystalloid) concluded that the type of crystalloid infused did not affect the incidence of AKI [46].
It was argued in the SPLIT trial that the severity of patients mirrored by the mortality rate (7.6 and 8.6% in the PlasmaLyte® and saline groups, respectively) and low fluid requirements was low (2.7 vs 2.6 l, respectively) and may have explained the absence of beneficial effects of PlasmaLyte®.
However, no method exists to assess or test the extent of carry-across effects in a split-mouth trial.
It involves a split-mouth trial and a parallel-arm design: patients who do not have symmetrical disorders (therefore are not eligible for the split-mouth RCT) will be included in the parallel-arm RCT.
