This work points towards the need to develop a spectrum of models, representing such variability as will be present in a patient population (Sarkar & Sobie, 2011).
A spectrum of models, from least to most complex, can thus be imagined, where the "most complex" and necessarily imaginary model has a one-to-one relation to real system it represents.
Our work looks at the extremes of a spectrum of possible models.
A wide spectrum of model experimental studies was covered.
However, recent studies in a broad spectrum of model organisms, including mice, have shown that not all functions of p53 are beneficial to a long healthspan [ 5].
These were designed to provide a hierarchical spectrum of model complexity, and parameter richness, with increasing partitioning of biologically reasonable sets of the data (Table 1).
A spectrum of the thermodynamic model includes rates of energy streams, exergy streams, exergy destructions and improvement potentials.
A multicondition model would also be more practically useful compared to a spectrum of disease specific models, as many patients have multiple comorbidities.
While there is a spectrum of dominant PHR models, (standalone, tethered, integrated), the authors state that only the integrated model has true transformative potential to strengthen consumers' ability to manage their own health care.
As a generalized scenario of stochastic programming, a spectrum of birandom programming models are developed to deal with birandom systems.
