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The optimum sampling design can be defined in two ways: 1. minimizing cost for a specified level of precision, or 2. minimizing variance for a specified cost.
minimizing variance for a specified cost.
In all areas of participation, the EU EC partnership (coordinated by the European Fusion Development Agreement) aims toward advancing the technology, while staying within a specified cost envelope.
It is also shown that this robust controller can achieve optimality under a specified cost function, which serves as the basic idea of the robust optimal control design.
The curve shows the probability that the ICER is less than a specified cost per QALY and, therefore, shows the probability that the ratio is cost-effective relative to any chosen ICER threshold.
minimizing variance for a specified cost. .
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The method then iteratively updates the location of the control points of the B-spline based on the specified cost function.
In designing a supply chain (SC) system, the problem arises when a company has unsatisfactory inventory control policy and material routing between supplier producer and distributor in SC considering specified cost and demand.
A few studies take on the more challenging task of determining the optimally cost-efficient strategy at a certain budget, on the basis of specified costs for collecting data at different stages, and specified sizes of the corresponding variance components.
Unfortunately, the US-based study by Weycker et al. [ 86] only specified cost-offsets due to prevented illnesses but did not incorporate vaccination costs.
However, in our literature review, the only Markov model that specified costs and outcomes in relation to duration on ART was Cleary et al [ 6, 22].
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