The lack of reproducibility observed at pH 5 may be explained by a poor specificity of the method or by a poor accessibility of IL-13 to capture and/or detect antibodies (for instance due to the presence of binding proteins).
We cannot discriminate whether this represents a higher specificity of the method (i.e., no/low detection of B-TRAbs or neutral TRAbs) or a lower sensitivity, since positive samples obtained with the other two methods were not tested with a BA.
The performance of WBC imaging is poor in spondylitis and spondylodiscitis: up to 50% of all patients with spondylodiscitis show photopenic lesions due to encapsulation of the infection, and therefore relatively hampered migration of leukocytes; as a result the specificity of the method is reduced [ 8].
Photodiode array detection was used as an evidence of the specificity of the method.
This sample size will also allow a precise quantification of: The specificity of the method (specificity estimation close to 75% based on both local studies) with a 5% precision; The area under the receiver operating characteristic (ROC) curve (estimation of 0.8) with an α risk of 5% and a precision of 0.02.
So, as a general approach, the researcher may choose first to identify critical residues based exclusively on a protein structure provided that the specificity of the method is quite good in that condition, and depending on the goal of the researcher it may be useful to run JAMMING using multiple protein structures.
Acknowledging official gene symbols are not necessarily mentioned in the literature of their respective gene aliases, the percentages above should not be mistaken as a measure of the sensitivity / specificity of the method.
To evaluate the performance of these methods, researchers first filtered the CPR artifact and then analyzed the rhythm using a SAA to obtain the sensitivity and specificity of the method, that is, the proportion of correctly diagnosed shockable and nonshockable rhythms, respectively.
The specificity of the method presented here is to use a fully multi-parameters equivalence method.
The specificity of the method as used in sheep tissues was checked against a wide range of related quinolone antimicrobials which were found to interfere with the 7-hydroxyflumequine analysis, but not with flumequine determination.
