Sentence examples for a specific target receptor from inspiring English sources

When drug action is elicited by a specific target receptor, it is important to kinetically clarify the relationship between them.

The interaction between the native or TBHP-treated MAb and the specific target receptor of MAb were measured by surface plasmon resonance using a Biacore T100 instrument (GE Healthcare Bioscience, Uppsala, Sweden).

For example, the kinetics of the association and dissociation of radioligands can be accurately examined from a simple tissue expressing the specific target receptors.

For this purpose, expression patterns of imatinib specific target receptors PDGFR α, β, c-kit and their according ligands PDGF A, B and H-SCF-1 were examined.

The development and progression of breast cancer are influenced by steroid hormones, particularly estrogen, via their interaction with specific target receptors.

Still, few examples in EC-related drug metabolism studies employ detection of biological activity [ 9, 10] and, to the best of our knowledge, none tested for a specific target enzyme or receptor.

We conclude that some MS lesions fail to remyelinate secondary to reduced OPC recruitment, and that chemotactic molecules are involved in the mechanism, providing a new group of drug targets to improve remyelination, with a specific target in the Sema3A receptor neuropilin-1.

There is no evidence for a sigmoidal curve that might suggest specific binding to a specific target, for example, a cell surface receptor.

A pharmacophore is a spatial arrangement of features that allows a compound to interact with a target receptor at a specific binding mode.

If the radiolabeled metabolites penetrate into the brain, signals of specific binding to a target receptor may be obscured by non-specific binding signals and hidden by background signal.

Targeting requires that a ligand on the nanoparticle surface interact with a specific membrane receptor on target cells.