Another interesting application for the TIPI system would be to use it as a method to deplete target proteins at a specific stage during a developmental process.
During the transdisciplinary research process, from the preconception phase throughout the research and knowledge translation stages, a rotating-role, multileadership model emerges in which the corresponding skill types are used according to what is required at a specific stage during the research project.
Such variation of importance reinforces one of the life cycle theory assumptions: a factor can have a beneficial influence during a specific stage and a negative one during another stage.
In fact, each tool uses its own form of data during a specific stage of the design process and its own set of questions.
Well-defined genetic influences, which are operational during a specific stage of behavioral development, provide a straightforward mechanism through which phenotypic variation can respond to selection pressures that arise predictably during an animal's lifetime.
CT is usually acquired during a specific stage of the breathing cycle.
Similarly, MAP3734c - 3736cmay also be employed during a specific stage in infection as iron from Fe-cMyco transfer to mycobactins in the cell surface has been reported, albeit in an in vitro setting only [ 113].
Aoki et al. report the isolation and characterization of a new fruit fly boundary factor that, unlike previously characterized factors, is active only during a specific stage of development.
Transcription of the A allele normally occurs only in the skin where transient A expression in hair follicles during a specific stage of hair growth results in a subapical yellow band on each black hair, causing the brown (agouti) coat color of wild-type mice (Duhl et al. 1994).
In general this is fine when the goal is to investigate the effect in chondrocytes generally, but when the goal is to investigate a factor at a specific stage, such as adulthood, or even during ageing, additional problems appear: how to restrict expression to a certain period of time.
At specific stages during spermiogenesis, a bundle of microtubules in the distolateral region of cytoplasm will transiently assemble around the nucleus to form a special structure called the manchette, which is believed to be indispensable for acquisition of the final nuclear morphology [7], [11], [12] and delivery of molecules to centriole and tail [13] [15].
