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The p-value was calculated using the hypergeometric distribution as the probability of n or more out of m genes having a specific GO Slim term, given that N out of M genes have that GO slim term in the whole genome.
Together these observations highlight that the HX motif is neither a unique nor an obligatory Hox protein interface for recruiting the PBC cofactor, suggesting that Hox-PBC interactions could rely on the presence of other specific SLiM s).
QSLiMFinder is designed to identify SLiMs shared between a specific 'query' protein (or segment thereof) and a group of proteins that interact with the same PPI partner.
MoRFs differ from ELMs and SLiMs in not depending on a specific sequence motif, but rather upon a pattern in a disorder prediction output.
"With great sensitivity and the slimmest of budgets, the architects have produced a specific environment for creative industries.
QuickGO not only filters annotations to a specific set of GO terms, but also allows the reaction or adaption of GO slims.
Our combined approach revealed that SLiMs are highly conserved in proteins from functional classes that are known to interact with a specific domain, but that they are not conserved in most other protein groups.
We detected signals of evolutionary conservation in SLiMs in proteins from functional classes that are known to participate in the signal transduction of a specific protein domain.
The annotated Gh-D-J sequences were further functionally classified using a plant-specific GO slim (Fig. 5).
Categorization is based on GO annotation and class sorting based on Plant specific GO slim terms (CateGOrizer tool).
These results indicate that the deacetylation partition groups are enriched for genes of specific GO Slim terms.
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