This diversity, combined with the large number of potentially acetylable lysines on histones, suggested the existence of a specific regulatory mechanism based on the substrate specificity of HATs.
However, without further specification, the principle provides only a rough outlook or orientation rather than a specific regulatory plan of action; its merits cannot be clearly evaluated unless a number of further questions are answered.
One or more governmental officials are handed responsibility for developing and overseeing a solution to the problem and a specific regulatory framework is set in motion.
After Wednesday's decision, those efforts are most likely to succeed if they are based on express language in a Congressional statute or a specific regulatory action that makes compliance with state requirements impossible.
Gene expression studies on a set of four selected genes revealed a specific regulatory pattern for the different compounds tested.
As both the supply and demand side of the market is strongly regulated it is difficult to evaluate the effect of a specific regulatory action.
The historical evolution of free ports underlines a growing complexification and specialization that has led to a multitude of models, each fitting a specific regulatory and operational framework.
While prior studies have analyzed the profession's efforts to shape its regulatory environment, few studies have examined the profession's pointed attempts to influence a specific regulatory policy that affects the practice of auditing in the United States.
As we know, CD4+CD25high T cells reveal a specific regulatory activity [13, 14], which is different from the conventional CD4+CD25low T cells with the positive immune response.
Beyond providing great insight into the biology of gene regulation, a combination of eQTL studies with results from traditional linkage or association studies of human disease may help predict a specific regulatory role for polymorphic sites previously associated with disease.
However, the quantitative performance goals recommended in ASCE/SEI 43-05 westablishedshed based on country-specific operating experience and seismic probabilistic risk assessment (SPRA) applications conducted for existing plants designed and operated to meet specific safety criteria, set by a specific regulatory body.
