Although the specific prerequisites for the successful application of self-regulation interventions such as the MCII strategy warrants further research, the present study is a first step towards identifying the approach's applicability to clinical populations.
Taken together, these data suggested that the localization may be a major prerequisite for specific biological roles of the histone isoforms in gene expression, marking distinct regions of chromatin distribution in the nuclei.
Using an eye-specific driver was a prerequisite for high expression.
The relatively high degree of flexibility within the L2 region may be a prerequisite for specific Hb binding to IsdBN1, supporting a "folding upon binding" model which is often observed for intrinsically disordered regions of proteins, and the plasticity of Hb-binding NEAT domain architectures.
Functional characterization of the fatty acid desaturase genes and their specific promoters is a prerequisite for altering the composition of unsaturated fatty acids of palm oil by genetic engineering.
Knowledge of the genomic bases of these specific features is a prerequisite for understanding the mechanisms underlying adaptation [ 1, 4, 5].
Unfortunately, while it is relatively straightforward to characterize MH diversity using traditional Sanger sequencing in species carrying a minimal MH system, researchers working on more complex MH systems have been unable to accurately screen MH allelic diversity and classify variation to specific loci, an essential prerequisite for more detailed investigations of selection.
The data indicate that the presence of a G-box element is not a prerequisite for leaf specific and light induced gene expression in sugar beet.
Expression of HLA class I/β2-microglobulin (β2-m) complexes carrying tumor-specific peptides is a prerequisite for adaptively matured cytotoxic T cells (CTLs) to be able to recognize tumor cells [ 7].
This indicates that some aspects of protein function violate the assumption that sequence determines a specific structure as a prerequisite for function, and is in line with other results reported recently [38].
