The study, called the National Lung Screening Trial, focused on a specific high-risk group: 53,000 current and former heavy smokers, aged 55 to 74, who had smoked for at least 30 pack-years.
Our study shows that the "personal" patients' needs are not identified with a specific high-risk group or with a unique genetic profile in the sense of genome-based "personalised" or "individualised" medicine.
Further studies are needed to resolve the problem of optimal treatment strategies, which still remain controversial in this specific, high risk group of women.
Vaccinating all groups at high risk of invasive pneumococcal disease with the 13 valent pneumococcal conjugate vaccine would have a large impact on budgets, therefore targeting specific high risk groups may be more attractive although this would require general practitioners to identify subgroups among those at increased risk.
9 We developed a cohort model to determine the cost effectiveness of vaccinating specific high risk groups with the 13 valent pneumococcal conjugate vaccine.
As a result, we were able to examine the association of ART-related AB with HIV-seroprevalence in the general population rather than targeting specific high risk groups through methods that did not employ random sampling.
Few studies were carried out to track the HIV-1 subtypes in Nairobi but these studies are relatively outdated, have dealt with limited sample size [26], [27], or have targeted specific high risk groups [28].
1 2 Currently, the World Health Organization and most countries prioritise specific high risk groups for vaccination.
There was insufficient data to provide evidence on predictive utility of the tests among specific high risk groups.
Focusing on specific high risk groups, in whom vaccination would be most cost effective, could reduce the costs substantially.
The risk behaviors of the HIV infected individuals are not distributed uniformly across the population, but tend to cluster in specific high risk groups.
