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But the proteins and signals that allow a cell to stay immature or commit to a specific fate are still unknown.
One such mechanism is DNA methylation, which is associated with gene silencing and is involved in a cell's progression towards a specific fate.
The differential expression of PCP within the epithelium, and notably not in the high density cells is additional evidence that these high density cells have a specific fate within the antenna, a fate we are suggesting is to develop into olfactory sensilla.
In addition ETV-6 is a transcription factor (Ets factor) increased by rIL-1β that results in differentiation and commitment of a cell to a specific fate.
First, genes associated with pluripotency should disappear at 0.4 mm because normally all lobe cells have acquired a specific fate (including the bipotent SPL) by this stage.
As stem cells become committed towards a particular cell lineage in response to positional information, they will adopt a specific fate and behaviour.
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Yoruba tradition follows a unique cosmology and asserts that every individual has a specific destiny and fate, placing importance on self-understanding, religious nourishment, and spiritual growth.
Compartment subdivision is induced primarily by the specific expression and activity of transcription factors that confer a compartment specific fate (reviewed in [4]).
Although cellular plasticity is one of the most exciting features of these cells, directing their specific fate efficiently presents a major challenge.
The question of whether intact somatic cells committed to a specific differentiation fate, can be reprogrammed in vivo by exposing them to a different host microenvironment is a matter of controversy.
However, these factors alone are not sufficient to drive differentiation towards a specific Th fate.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com