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Alan Sepinwall of HitFix wrote about the "palpable, painful sense of dread throughout this episode", stating: "Though Lane's tax trouble seemed to come out of nowhere a few weeks ago...all of his behavior, and Don's, felt very true to form, and not like characters acting in a way designed to create a specific end point.
By comparison, an RPF is determined for a specific chemical in a single study relative to a specific end point.
The domain could be, but is not necessarily, considered a specific end point within the overall conceptual model.
Antitumour activity against melanoma was not a specific end point in our trial, which also included patients with other solid tumours and patients with nonmeasurable disease.
One of the few epidemiologic studies to link low-level human exposure to an environmental contaminant with a specific end point was Swan and colleagues' investigation of prenatal phthalate exposure, published in the August 2005 issue of EHP.
When relevant, a copy of data from hospital admissions was obtained for use by the committee deciding on the presence or absence of a specific end point using predefined criteria.
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Natural phenomena, including living things, constantly change and, further, this change is neither purposeful nor directed toward a specific end-point.
We believe that the explanation for this observation lies with the sample size of the study, which was powered to detect a difference using the most sensitive and least specific end point and that had our numbers been larger we would have shown equivalence for both the alternative, more specific end points.
Because a detailed analysis of all these untoward effects was beyond the scope of this workshop, we selected the specific end point of testicular function for a more detailed analysis.
Depending on how the data are analyzed and the specific end point selected, dronedarone may or may not appear to be a more successful drug in the management of atrial fibrillation.
In subsequent BPA and di-n-butyl phthalate studies, large intralitter variability of this specific end point was apparent when the VP weights from entire litter complements were examined.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com