The phrase "a specific driver in" is correct and usable in written English.
It can be used when referring to a particular factor or element that influences or causes something within a certain context.
Example: "In our analysis, we identified a specific driver in the decline of sales last quarter."
Alternatives: "a particular factor in" or "a distinct influence in".
Analysis of a large number of patients is necessary because if a specific driver mutation is present in only 7%% of patients, 700 patients need to be evaluated to detect this mutation in 50 patients.
Microscopic driving states were categorized into different clusters, and it was found that the risks are distinct in different clusters and a specific driver might experience different risks in car-following process.
The best manifestation in the context of climate change would be to experimentally manipulate a specific candidate driver in nature, such as through artificial warming of the environment experience by a natural population.
By contrast, a model of paediatric cancers posits that, in some cases, a single, specific driver alteration might promote cancer development in certain cell lineages, if it results in aberrant gene expression during a crucial period of development6.
Of particular importance is the identification of uniquely expressed genes that may serve as tissue-specific drivers in transgenic constructs or potential knockout targets in the next generation of insect control agents.
Identifying the specific driver genes targeted in a particular cancer remains a challenge given the multiple possible reasons for selection of an LOH event.> Additional file 1: Table S1.
This in turn has led to the development of targeted therapies based on specific driver mutations found in a given tumor type.
Together, the gene-set based analysis of GWAS data and the subsequent replication attempt might indicate that common genetic variation in specific driver kinase loci, and particularly in EPH receptor genes, influence risk of breast cancer.
However, current evidence indicates that the specific driver of PARP1 expression in breast cancer still unknown.
Within these broad categories, alterations in specific driver genes are believed to produce the heterogeneity observed amongst and within breast tumor subtypes.
