Sentence examples for a specific disruption from inspiring English sources

The model-algorithm method can handle large-scale problems, but it has to predefine a specific disruption and a specific distribution state for constructing a model and algorithm, which is inflexible, time-consuming and consequently unable to promptly obtain solutions for responding to different disruptions in real time.

The levels of ATG5 on the other hand were not significantly changed, arguing for a specific disruption of the PI3K complex in AD rather than a general deficiency in the autophagy pathway and signaling cascade.

Functional studies demonstrate a specific disruption of endosome lysosome fusion but not protein sorting by the MVB.

Transgenic mouse dams with a specific disruption in 5-HT neuron development display profound maternal deficits (Lerch-Haner et al. 2008).

We took advantage of a specific disruption of the retinotopy in the superficial layers of the SC that has been observed in the Isl2-EphA3 knock-in mice (Fig.  1; Brown et al. 2000).

It remains difficult to determine whether the reduction in exocytosis after treatment was the result of a specific disruption of cortical actin or whether it was the result of a more general actin disruption.

A hepatocyte specific disruption of Bcl-xL, an antiapoptotic member of the Bcl-2 family, leads to continuous hepatocyte apoptosis and later liver fibrotic responses.

Thus, a more specific disruption of myelin is implied when an increase in RD occurs without an accompanying increase in AD (cf., Madden et al., 2012).

However, this also suggests that hypoxia has been an important obstacle for C. pneumoniae survival, given that the minimalist genome of Chlamydia species maintains a commitment to specific disruption of this signaling pathway.

Directly inhibiting or activating the function of a transcription factor requires specific disruption or recruitment of protein protein or protein DNA interactions.

With use of a Cre-loxP method, specific disruption of either HIF-1α or HIF-2α in osteoblasts revealed similar roles for both isoforms in VEGF-dependent promotion of bone vascularization, whereas only HIF-1α HIF-1αed bone formation by direct stimulation of osteoblast promotedation (4 – 6).