To help overcome those, the circumstances when gains are likely to be large need to be identified and a push made for specific coordinated outcomes in such cases.
NO was found to trigger a specific and coordinated cell cycle arrest independent of both cGMP and cAMP.
For example, MYB28, 29 and 76 exerted a specific and coordinated control on the regulation of aliphatic GS biosynthesis, while MYB34, 51 and 122 could regulate the synthesis of indolic GS [ 49, 50].
The functional cerebral systems model proposes that there are specific coordinated regions of the brain that are utilized to complete certain tasks.
Skeletal myogenesis requires the occurrence of specific coordinated events, including exit from the cell cycle, transcription of muscle-specific proteins, fusion into polynucleated fibers and assembly of the contractile apparatus.
Collectively, these results demonstrate that NO, independent of cGMP and cAMP, triggers a specific and highly coordinated genetic program that alters the G1/S transition and induces arrest in early G2/M (Fig. 8).
In summary, in contrast to the coordinated temporal regulation of Lef1 alternative splicing, Tcf7l2 events showed remarkable tissue-specific coordinated regulation, with the predominant isoforms in the thalamus lacking exon 4 and including exons 13, 14, and 16 translated to TCF7L2 with a truncated C clamp.
All together the data support the hypothesis that ERFs are the main component enabling ethylene to regulate a wide range of physiological processes in a highly specific and coordinated manner.
The "union" bar in a specific pathway indicates the coordinated downregulation of the pathway by all co-expressed miRNAs whereas the "intersection" bar reflects and overview of the cooperative downregulation of single genes by all of the expressed miRNAs.
The stepwise formation of the biofilm, such as developmental processes, involves the switching on of a specific genetic program, leading to coordinated patterns of gene expression and protein production.
