Sentence examples for a specific binder from inspiring English sources

This led to the development of hybridoma technology allowing, at least theoretically, for an unlimited production of a specific binder.

In a search for small molecule compounds to selectively perturb TFIID function, we identified a tin-based metal cluster as a specific binder and modulator targeting an IDR within the TAF2 subunit of metazoan TFIID.

Under basal conditions, both proteins localize primarily to the mitochondria, where the anti-apoptotic proteins (enhanced green fluorescent protein (eGFP -BCL-2, eGFP -BCL-2, or eGFP -BCL-23B)) sequester theGFP-BCL-XLptotic counteGFP-MCL-1 3Brry-BAD or mCheGFP-MCL-1 3BΔC, eGFP-MCL-1 3Bing a sequesterbinder of MCL-1).

An ideal scenario would be to have a highly specific binder for each of the main PSP toxin groups.

The results thus showed that de novo design can be an alternative approach to yield high affinity in silico scFv designs as a starting point for antibody or specific binder discovery processes.

These marks maintain the epigenetic information and serve as interaction sites for specific binder or reader proteins, which include epigenetic modifier enzymes, repressors, chromatin remodeling complexes and the transcription machinery.

Since charge compensation for the Lys surface patch was crucial, we also tried to add the amine coordinating bisphosphonate ("lysine tweezer") 1 (Scheme 1), which is known to be a Lys-specific binder, resulting in high resolution crystals.

Specific binders display a differential SILAC ratio, whereas background binders have a 1 1 ratio.

αRep proteins therefore seem to be ideally suited to serve as specific binders in a eukaryotic cellular context.

To demonstrate that a specific ccFv phage could be selected from a ccFv phage display library, we constructed a "doped library" and panned for specific binders.

Therefore, EDTA-mediated recovery of aptamers is an effective process to distinguish specific binders from nonspecific adsorbates.