Sentence examples for a specific backbone from inspiring English sources

Each set of parameters fits in a specific backbone sequence.

The high conservation of these residues in the CHHC Zn-finger domains may reflect a requirement for a specific backbone conformation.

In contrast, immunisation with Theratope, thus making the immunogen independent of a specific peptide backbone, did result in a significant delay in tumour development.

These findings obviate the possibility that this effect was mediated by a specific vector backbone or due to the random integration event.

Previous studies have revealed that specific backbone conformations are likely to be a part of ligand-binding site and that the magnitude of dihedral angles may undergo slight changes after ligand binding [ 13, 15, 19]; however, no method has considered the conformation of amino acids in ligand-binding site prediction.

Instead, small elongations produced by the force weaken specific backbone H-bonds with respect to water-backbone H-bonds.

The amino acid specific backbone dihedral angle distributions determined from the ensemble selections show that negligible secondary structure is present.

Functional titration methods such as FACS analysis after limiting dilution cannot be used in this case, since this titer is dependent on the specific backbone.

In addition to the identification of ligands that associate with the N-labeled protein, the changes in residue specific backbone shifts, which can be quantified to derive ligand stoichiometry and affinity, can also be used to locate the ligand binding site on the protein.

Additionally, in pandemic response simulations, "mock up" or example vaccines (in a specific DNA plasmid backbone) and patch delivery system could be submitted for approval by the FDA, and this formulation would be evaluated in the clinic for immunogenicity that recapitulates the influenza correlates of protective immunity already defined by CBER and EMA.

For structure determination, N-edited Nuclear Overhauser Enhancement Spectroscopy (NOESY) and C-edited NOESY spectra with 150 ms mixing times were recorded on a Brucker AVANCE 900 spectrometer at 296 K. Sequence-specific backbone chemical shifts were assigned using standard triple-resonance experiments (59).