In VAChT, a human vesicular acetylcholine transporter, a member of DHA1 family, six glycine and proline rich motifs are predicted to promote the formation of special backbone conformations including kinks in TMS, tight interactions between TMS and very flexible β-turns.
To extend the applicability of FISH to living cells, special backbone-modified probes and specific conformations (molecular beacons) have been designed.
A special kind of structural deficiency, the exposed backbone hydrogen bond (EBHB) is identified in soluble proteins with PDB-reported structure [4], [6], [18].
Be it locals looking for aa hilarious brunch, or tourists looking for a special slice of New York City, these gals are the backbone of the New York City's drag scene.
A special fold tree [10] is created to constrain backbone movement to the designed site, i.e. there will be no conformational changes in regions that are neither repackable nor designable.
The unique nature of the proline side-chain imposes severe constraints on the polypeptide backbone, and thus it seems likely that it plays a special structural or functional role in the architecture of proteins.
The high level of graduate unemployment is a special worry because studies of court records show that well-educated Tunisians form the backbone of homegrown jihadi groups.
The residues p6G and p8R form a special pair such that any canonical TCR contact will necessarily involve both of them, as well as the peptide backbone of p7E (Fig. 5A).
Dodd decides to make poor, muddled Freddie a special project of his, but his failure to indoctrinate his new disciple, to exert his mastery over this troubled man's mind forms the backbone of this gripping and deeply mysterious drama.
Green Bay is truly a special, special situation.
