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The persistent recruitment of activated T cells to male genital organs is likely to increase the tissue viral load by providing a source of target cells for the virus.
Bacteria were extracted from each soil sample using the following procedure: 1 g soil was suspended in 10 mL distilled water in a 50 mL centrifuge tube (BD Biosciences) and vortexed for 10 min. After stationary incubation for 10 min at room temperature, the supernatant was used to evaluate the medium as a source of target bacterium and soil saprophytic bacteria.
The NK-sensitive K562 line was used as a source of target cells.
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The relevance of the Slt regulatory pathway to cell structure, intracellular trafficking and cation homeostasis and its restricted phylogenetic distribution makes this pathway of general interest for future investigation and as a source of targets for antifungal drugs.
In this review, we have summarized the present state of knowledge on pathways of amino acids biosynthesis in human pathogenic fungi as a source of targets for antifungal chemotherapy and on compounds inhibiting particular enzymes of these pathways as potential antifungals.
Ammit, A.J. Glucocorticoid insensitivity as a source of drug targets for respiratory disease.
As a result, mitochondrial bioenergetics has become a source of therapeutic targets in predemented stages of the spectrum [ 12, 13].
In a similar fashion as described for PCR assay design, genomic sequences can be a source of genotyping targets.
Thus far, 11 PDE families have been described, most of them are expressed in the brain, attracting attention as a source of new targets for the treatment of psychiatric and neurodegenerative disorders.
As a proof of principle, total RNA derived from human and bovine fetal brains was used as a source of labelled targets for hybridisation onto a human cDNA microarray composed of 349 characterised genes.
Just like goal-directed resuscitation, based on pathophysiology and now a source of therapeutic targets [ 3], epigenetic modifications could very well be the future for care of patients with MODS: epidrugs are coming.
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