More interestingly, we demonstrated that photodegradation products of glabridin would be a valuable source for discovering new tyrosinase inhibitors with higher activity and better stability.
Metagenomic libraries are a powerful source for discovering new biological activities and have already been successfully used to isolate novel hydrolytic enzymes such as amylases, cellulases and xylanases [ 6, 7].
Unrelated compounds belonging to different chemical classes (benanomicin, coumermycin, N-butylbenzensulphonamide, and halogenated spirotetronates) have been recently discovered as products of Actinoallomurus spp. [ 24, 25], confirming that this novel genus represents a promising source for discovering novel bioactive metabolites when targeted with selective and efficient screening strategies.
Farrell and Zhang et al. [ 7] found that salivary microbiota serve as an informative source for discovering noninvasive biomarkers of pancreatic cancer and chronic pancreatitis.
While such 'no-call' or false-negative errors in parents can be ameliorated somewhat with higher sequencing depth and/or more comprehensive variant-calling strategies, larger and more comprehensive pedigrees provide a powerful, complementary source for discovering and studying human genetic variation.
Our results indicate that GeneRIFs are an excellent data source for discovering disease-gene relationships.
If you've seen the semi-controversial (well, at least in the art world) Bravo reality series Work of Art, then you're going to love this new curatorial site ARTorNOT—"the world's premier source for discovering if a form or concept is ARTorNOT".
The use of the aforementioned E. coli ASKA collection, in a high-throughput format, provides one source for discovering latent enzyme activities.
One potential source for discovering novel molecular mechanisms that protect against malignancy is a longevity model, because a major cause of premature death in mice can be attributed to this disease process.
An alternative source for discovering such drugs is natural products.
