Sentence examples for a sound validation from inspiring English sources
However, disappointingly few biomarkers were approved for the detection of unrecognized disease, and even approved markers may lack a sound validation phase.
Many information scientists plead for a sound validation of Google Scholar and other developing tools before advertising them.
These similarities in mutation frequency in the latter genes provide a sound validation of and positive control for our methodology, for both the experimental approach (tumor content, library creation, and sequencing) and bioinformatics pipeline.
In the present work, a further, more sound validation of the new model and simulation code is accomplished to govern two-dimensional systems.
Before nonanimal toxicity tests may be officially accepted by regulatory agencies, it is generally agreed that the validity of the new methods must be demonstrated in an independent, scientifically sound validation program.
We propose an objective, accurate and biologically sound validation scheme for core promoter predictors.
This document argues for a cautious expansion of the scope of prenatal screening to serious congenital and childhood disorders, only following sound validation studies and a comprehensive evaluation of all relevant aspects.
Data from an RCT and availability of specimens from a large number of patients are both essential for a sound retrospective validation, as otherwise it is impossible to isolate any causal effect of the marker on therapeutic efficacy from the multitude of other factors arising from a non-randomized design and/or selected samples [ 24, 25].
With the aim to develop a sound DIA validation and calibration methodology, we designed our experiment to test and improve the accuracy of Ki67 LI estimation by automated DIA on preselected tissue microarray (TMA) Ki67 IHC images, with the ground truth obtained by counting tumour cell profiles using a stereology test grid of systematically sampled frames.
OpenTox provides scientifically sound validation routines for the determination of these measures.
This paper is one attempt to achieve sound validation for four different methods of prediction, one of which is finite-element analysis.
