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The therapy emerged from a sophisticated effort to reverse-engineer gene networks to identify genes that drive cancer.
Officials said the prisoners burned some documents and photographs, and took others with them as they fled, suggesting a sophisticated effort to remove themselves from official records.
"The real danger here is that they will mount a sophisticated effort to penetrate or assault one of our camps or bases with a ground element," he said.
It is a sophisticated effort to demolish the idea of a press independent of political parties by way of discouraging scrutiny of conservative politicians in power.
The Group of 30 study, which was led by Dennis Weatherstone, the chairman of J. P. Morgan & Company, was a sophisticated effort to do just that.
Phones and telemarketing have eaten up at least $24 million, and Internet advertising $36 million, part of a sophisticated effort to try out different fund-raising appeals, test attacks on Mr. Romney and reach small donors.
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It would seem a more likely bet for breakout success, being both a shorter and a more sophisticated effort, and it's packed with all those ingredients — chiefly sexual violence and a plot gesturing vaguely at Europe's troubled political history — that audiences here tend to look for in a foreign favorite.
A more sophisticated effort, though, relied on intercepting Google Maps queries made on smartphones, and using them to collect large volumes of location information.
According to people familiar with the 2007 case, investigators also found evidence that BP traders had previously engaged in a more sophisticated effort to manipulate the much-larger crude oil market, by moving oil in and out of its gigantic storage facility in Cushing, Okla.
Strengths of the study were that the investigators made a concerted, sophisticated effort to promote state-of-the-art end-of-life care, and that clinicians highly rated the educational and training components of the intervention.
Probably the most sophisticated effort from a legal standpoint is a document titled "A Treatise on the Law of the Use of Weapons of Mass Destruction Against the Unbelievers," written in 2003 by a brilliant Saudi dissident named Sheik Nasir bin Hamad al-Fahd.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com