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Relative to smaller DNA fragments, larger DNA fragments are more likely to participate in transient intra-molecular complexes between boron species and non-vicinal phosphate groups (perhaps located far apart along the DNA backbone), thus altering the DNA secondary structure so that it mimics a smaller apparent length during gel separation, figure 1A and 1B.
These results show that exocytosis of the primed vesicles in the RRP is significantly impaired (resulting in a smaller apparent RRP) in the cells expressing K502R RIM1α.
One of them, spot number 445, was only observed at pH 4.5, indicating a smaller apparent molecular weight and higher p I than expected (SD1, Fig. S2; S23).
The expression of ICAM-1 with a smaller apparent molecular mass of 72 kDa was induced by silibinin and that with 55 kDa was induced by tunicamycin in TNF- α-stimulated ARPE-19 cells.
Our previous regime, based upon pharmacokinetic studies, indicated that lower doses were warranted due to a smaller apparent volume of distribution in the children, and that a higher dosage regime was justifiable for adults and in areas where quinine-resistance was more problematic [ 19].
Neither gel filtration nor sucrose density gradient centrifugation can be used in isolation to obtain the molecular weight of the MLD as the presumed elongated nature of the protein will result in a larger apparent Stokes radius and a smaller apparent sedimentation coefficient as compared with a globular protein.
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Adjuvant adsorption produced only a small apparent change in secondary structure, while significantly stabilizing the protein to thermal denaturation.
Something that brazen, which could offer the Patriots only a small apparent advantage, told other teams that Belichick might try anything to get ahead.
It was also confirmed that the kinetics were slightly accelerated by a limited increase in temperature with a small apparent activation energy of reaction equal to 22 kJ mol−1.
There was a higher proportion of subjects reporting their source of avian influenza information from village chiefs (+5.6% in Prey Veng, p = 0.001; +4.5% in Kampong Cham, p = 0.01), and a small apparent decrease from health centers in Prey Veng (−6.2% in Prey Veng; p = 0.002), and village animal health workers (−7.8% in Prey Veng, p = 0.001; −6.4% in Kampong Cham, p = 0.004).
The exonuclease resides ca. 45 Å from the polymerase active site with a small apparent hole between the two.
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