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Though InterMune initially envisioned using the drug to treat infectious disease or cancer, its plans changed in 1999, when a paper published in The New England Journal of Medicine reported striking results from a small trial for pulmonary fibrosis.
Additionally, vincaria has successfully completed a small trial for osteoarthritis of the knee demonstrating a rapid reduction in pain and improved function [ 47].
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For example, a small trial of cognitive behavioral therapy adapted to address diabetes-relevant behavior change improved both glycemic control and diabetes distress in adults with poorly controlled type 1 diabetes, compared with a control condition, with benefits maintained over 1 year of follow-up (23).
Recently, Promrat et al. (24) reported the results of an smaller trial of lifestyle intervention for 31 overweight patients with biopsy-proven nonalcoholic steatohepatitis, and their results are in agreement with our findings.
20 21 None of these, except for a small trial using sigmoidoscopy, 22 were evaluated for their effect on mortality.
They approached Asda to suggest a small trial in store – filmed for the programme – to gauge customer perceptions of wonky produce and whether they would be willing to buy it at a discount.
For example, a small trial in 22 patients with rGBM reported a mOS of 8.2 months for the combination of doxorubicin with TMZ.
It is unusual for such a small trial to show a difference in heart attack rates.
"This is a small trial, but it still is exciting for a number of reasons.
I feel that that was a smaller trial run for what we're going to be seeing right now".
There is significant heterogeneity within the patient populations of these small trials, for several reasons.
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