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The phrase "a small region of" is correct and usable in written English.
It can be used when describing a specific, limited area within a larger context, such as geography, biology, or any field where spatial dimensions are relevant.
Example: "The study focused on a small region of the rainforest that had been affected by deforestation."
Alternatives: "a limited area of" or "a minor section of".
Exact(60)
Spatial dynamics of pertussis in a small region of Senegal.
This endangered hummingbird is found only in a small region of Peru.
Synthetic compounds used in drug discovery are limited to a small region of structural space.
This is a small region of the forward part of the brain called the suprachiasmatic nuclei.
It was one of six camps that have been a drain on Ingushetia, a small region of 350,000.
About half of it remains wooded; in the south lies a small region of iron ore deposits.
On the other hand cut cells only appear in a small region of the domain.
Finally, a small region of left IPS was also activated by motor orienting for manual, though not saccadic, responses.
Main effects of lexicality (word > pseudoword) were isolated to a small region of the left lateral prefrontal cortex.
I first describe a neural network model of associative memory in a small region of the brain.
Negroland is my name for a small region of Negro America where residents were sheltered by a certain amount of privilege and plenty.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com