A decade later, we could validate in a small prospective mechanistic study these findings [ 47]: pre-treatment biopsies in patients with metastatic melanoma who subsequently responded to systemic IL-2 administration displayed a pre-existing pro-inflammatory status.
In a small prospective study assessing 10 symptomatic and 10 asymptomatic subjects, Schellhas et al. compared cervical discography to magnetic resonance imaging.
This is in contrast to a small prospective study in 2004, where only 13%% of radiologists identified the same [9].
This finding was confirmed by a small prospective randomized control study by Bourgoin et al. involving 28 patients [22].
We undertook a small prospective randomized controlled study to evaluate the PEG spray on adhesion formation in women undergoing common laparoscopic gynecological procedures.
The primary limitation of our study was that it was a small prospective comparative study including a small number of patients and done at a single center.
In a small prospective study of 108 real-time cases, 41 intussusceptions were identified on ultrasound and analysis of bowel wall motion indicated early resolution.
Polo is considered a high-risk sport, but in the only previous report, a small prospective study of elite players in Argentina, the incidence of injury was 7.8/1,000 playing hours [1].
Similarly, in a small prospective cohort of 42 patients with ARDS (mainly due to sepsis), endocan concentrations (1 day after the diagnosis of ARDS) were higher in non-survivors than in survivors [19].
Conclusion Based on a small prospective observational pilot study, a HEP score ≥5 could have a higher predictive value than a 4T score ≥6 in the early diagnosis of HIT in SICU patients.
In a small prospective study involving septic shock patients requiring norepinephrine to maintain MAP above 70 mmHg, prostacyclin (PGI2 or iloprost) infusion showed improvement in both cardiac output and hepato-splanchnic blood flow [37].
