Analogous results could be found when we calculated the same data in the analysis for survival, with only a small difference; the localisation also reached a P-value <0.02 (expected risk 1.7, 95% CI 1.1 2.6).
Although there may be a dissociation between detection and localisation on a small proportion of trials, we find a number of factors that lead to the underestimation of localisation including stimulus variability, response imprecision and participant guesses.
Overall, our data suggest that although it is possible that there may be a dissociation between detection and localisation on a small number of trials, particularly on easy trials (low density), there are other plausible explanations for the majority of such apparent dissociation trials.
localisation of small tumours localisation of multiple tumours, particularly in MEN 1 detection of small tumours in the pancreatic head, which may be difficult to palpate at surgery detection of tumours arising in the duodenal wall detection of lymph node enlargement to improve staging accuracy accurate depiction of the relations between vascular and biliary structures and the tumour.
Intense hypermetabolism on FDG-PET corresponds with localisation on CT in a small right supraclavicular lymph node, clearly indicating recurrent lymphoma.
In some cases, imaging with somatostatin receptor scintigraphy may help in the localisation and characterisation of a small peripheral lesion (see below).
This allows the approach to be implemented in challenging time-critical scenarios, such as in the localisation of artillery firing events, for which there may be only a small window of opportunity in which to perform a retaliatory strike.
There is a small family of KAP-αs, six in Homo sapiens and one in Saccharomyces cerevisiae, which recognise nuclear localisation signals (NLS) on cargo and bind to a member of the larger KAP-β family [5].
Our results show that a small defined region in tail of budding yeast myosin II, the MLD, is necessary and sufficient for localisation.
Thus, the pattern taken from a small number of trials suggest that in the difficult images, such as our set of high-density mammograms, apparent 'detection without localisation' responses can be accounted for by 'lucky' guesses.
