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However, in optineurin depleted cells level of polyubiquitinated RIP was higher and overexpression of CYLD resulted in only a small decrease in the level of ubiquitinated RIP (Figure 6A).
Single-agent atRA at 1 μM caused a small decrease in the level of RARα.
As detailed above knockout of Cyp27a1 results in a small decrease in the level of 24S,25-epoxycholesterol 24S,25-epoxycholesterol
Our data suggest that Y766F is associated with a small decrease in the level of discrimination against rNTPs, too small to be detected in an earlier screen for rNTP incorporation.
CHK1-depleted HCT116 p53−/− or SW480 cells treated with thymidine show a pronounced decrease in the level of pSer10-histone H3 after treatment with ZM447439 but only a small decrease in the level of cells with a subG1 DNA content.
There was a small decrease in the level of intact PARP at 48 h, with a 26 and 20% decrease compared with cells at 0 h in two independent experiments, with the level of uncleaved PARP becoming almost undetectable at 72 h.
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Finally, the absence of MYB28 and MYB29 transcripts resulted in a small decrease in the transcript level of MYB76 (Figure 7C).
S155A had a small decrease in the efficiency of DNA elongation (85% the level of the wild type reference).
This reduction in mRNA levels is accompanied by a small decrease in the methylation of repetitive intercisternal A particle DNA elements.
Eighty-eight probes with a small decrease in expression levels from 4 h pi were found in the first cluster and 45 probes with a stronger decrease in expression levels from 2 h pi in the second cluster.
At two time points (30' and 45') there was a small decrease in nuclear levels of RelB in IL-10 treated cells which was not sustained at the 60' time point.
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