Additionally, the hypoxic threshold for regulon induction was attained with 2 mM AA which is expected to exert a slower effect on redox change compared to 10 mM AA (see methylene blue data, Figure S3 panel A), further indicating the role of O2 depletion, rather than other redox effects, in inducing the regulon.
Thus, ChEI treatment might have a slowing effect on the rising costs of community-based care.
However, if threat cues have a slowing effect on RTs, as well as an attentional cueing effect, both should be taken into account when interpreting the results.
In a second study, a slowing effect on the rate of PSA after 3 months of treatment with celecoxib was observed.
Correcting for normal aging may be particularly important when the healthy group declines over time since a disease-modifying treatment effect is not likely to be able to slow normal aging effects even when it has a slowing effect on disease-specific decline.
However, on spatial cueing tasks, differences in RT between threat cue and neutral cue trials may stem from a slowing effect of threat on RT, as well as effects on allocation of visuospatial attention.
Thus, a difference in RT between these conditions could reflect two separate effects, i.e., a slowing effect of threat on RT and a difficulty in disengaging attention from the threat stimulus.
That is, differences in RT between threat cue and neutral cue trials may result from two separate effects: (i) a slowing effect of threat cues on motor responses, which may reflect a temporary inhibition of ongoing activity, and (ii) an effect of threat stimuli on allocation of visuospatial attention.
This is probably due to the slow effect on LSD1 downregulation mediated by Li or shRNA alone.
Details, details! Staying on a ranch, riding horses, corralling cattle and cooking by the campfire had a profound slowing effect on me.
