The best fit is obtained using slow correlation times exceeding 80 ns which corresponds to the "rigid" limit in X-band EPR.
The pattern of correlated firing across cell types was similar at photopic and scotopic light levels, although additional slow correlations were present at scotopic light levels.
Actually, without the assumption of a slow input, lagged correlations of the input appear in the averaged system.
The dynamics of hydration water can be detected by a series of experimental techniques, which show that hydration waters typically have slower correlation times than water in bulk.
Membrane proteins exhibit a broad time scale of dynamics and these motions highly influence the function of the protein: The residues in transmembrane segments generally undergo restricted motion on a fast time scale (picosecond-nanosecond), while soluble domains show large amplitude motions with slower correlation times.
After the release is complete, we observe a slow relaxation of the correlations (see hDAT3TT1Run2 in Figure 9 ), with the coupling between ICL4 and the S2 site remaining the highest among all the correlations considered.
The structural context of Gly has been noted above as corresponding to the residue preceding the conserved cis-proline residue in catalytic redox-active Trx domains, and this residue also shows up in the relaxation data as having an unusually slow internal correlation time.
Since rain attenuation is a slow fading process that exhibits spatial correlation over tens of kilometers [53], we assume that users among different beams undergo independent fading.
Although the initial observation was a correlation between higher affinity and reduced receptor agonism, further analysis showed a clearer correlation between a slower rate of dissociation and reduced agonism.
However, if a small-molecule ligand binds to a macromolecule, it assumes the overall slow rotational correlation time characteristic of the macromolecule, resulting in the NMR signals broadening.
