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Binding of αH6 leads to an inhibition of ADP-stimulated respiration (state 3 respiration) associated with a slight uncoupling of state-4 respiration.
In particular, αH6 interacts with mitochondria through electrostatic interactions involving the lysines 157 and 158 and immediately induces an inhibition of state-3 respiration and a slight uncoupling of state-4 respiration.
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This may account for the slight uncoupling of Pcellmax and αcellmax (Figure 3B): maximal carbon fixation via the Calvin cycle may occur before maximal light utilization due to the offset in timing of the synthesis of the proteins involved (Figure 6).
Consequently, we can conclude that H2O2- (ex vivo TBHP-) activated or PA-induced (vide infra) iPLA2γ cleaves FAs off mitochondrial phospholipids and provides them to UCP2 as the transport substrates, ensuring slight uncoupling of mitochondria.
Raices M, Maruyama H, Dillin A, Karlseder J. Uncoupling of longevity and telomere length in C. elegans.
There was a slight smell of incense.
Just a slight chance of afternoon showers.
I have a slight fear of flying.
This represented a slight fall of 100,000.
Kevin McNaughton has a slight chance of playing.
They have a slight conflict of interest.
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