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When the concentrations were higher than 2.0 mM, a slight decrease in cell survival rates was detected.
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Our study shows that activation of RLRs markedly reduces the viability of MSCs, whereas activation of TLRs has no influence on MSC survival, except for TLR3 activation induces a slight decrease in cell viability, indicating that RLR signaling is critical in controlling MSC survival.
Also no indication of a cytotoxic effect was observed in the presence of TAT-SA-complexed, biotinylated PPAA (4 μM) at 4 24 h post transduction and only a slight decrease in cell viability was detected at 48 and 72 h post transduction (94.0% ± 3.8% survival) compared to untransduced control cells (100.0% ± 3.3% survival).
We observed a slight decrease in cell viability (83.6%) compared with control MSCs cultures (89.8%).
In Saos-2 cellsPDH2 cells only the highest MPA concentration induced a slight decrease in cell viability.
However, we observed a slight decrease in cell number in Scd1-treated NHDF that a block or a slower rate of proliferation could explain.
Pd-Spm also resulted in a slight decrease in cell number in L56Br-C1 cells.
Each inhibitor triggered a slight decrease in cell growth in MALME-3M cells.
Immediately after exposure, DOX alone resulted in a slight decrease in cell viability (-4.15%).
At concentrations of 20 30 μg/ml, a slight decrease in cell viability was observed (Fig. 1a).
Cells transfected with miR-215 showed a slight decrease in cell proliferation when compared with control cells (Supplementary Figure 1A).
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