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The phrase "a sizeable separation of" is correct and usable in written English.
It can be used when describing a significant distance or difference between two or more entities, whether physical or abstract.
Example: "There was a sizeable separation of opinions among the committee members regarding the proposed changes."
Alternatives: "a significant gap of" or "a considerable distance of".
Exact(1)
The formation of gap for the half-metal compounds was discussed by Galanakis et al.[17] for Co2MnSi, which is due to the strong hybridization between Co-d and Mn-d states, combined with large local magnetic moments and a sizeable separation of the d- like band centers.
Similar(59)
The sizeable separation between the N-termini of the TM helices in the head-to-head dimer predicts that the stabilisation of the aTKD dimer, by enforcing the N-crossing TM dimer40, would break the head-to-head interaction.
However in atmospheric air, even with a small inter-electrode separation of less than 1 mm, a sizeable voltage (upwards of 4 to 5 kV) may still be required to initiate breakdown.
Due to the large magnetic moment of an unpaired electron, the effect is detectable for sizeable separations (up to ∼34 Å for Mn2+).
Older people represent a sizeable population of the UK.
That's a sizeable fraction of that group's success.
It keeps a sizeable amount of cash off the books.
But there have been a sizeable amount of stinkers, too.
A sizeable number of Tory MEPs are anti-European zealots.
A sizeable chunk of the $13bn relates to customer redress.
The mixer proved to be a sizeable dose of LSD.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com