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The phrase "a sizeable reduction of" is correct and usable in written English.
It can be used when discussing a significant decrease in quantity, amount, or degree of something.
Example: "The company reported a sizeable reduction of costs in the last quarter, leading to increased profits."
Alternatives: "a significant decrease in" or "a substantial cut in".
Exact(2)
Both were made possible by a sizeable reduction of public spending following upon restrictions in social security.
Loss of atf1 resulted in a sizeable reduction of H3K4me3 levels throughout the central cores and rDNA array.
Similar(57)
For both reforms, we find a positive effect on DHI of about 1%, a sizeable reduction in the number of poor households (3.14 percentage points under the EITC and 3.86 percentage points under the WTC), and a small improvement in the living standards of those who remain poor.
Furthermore, a too thick CuInS2 film may dramatically reduce the amount of light absorbed by the (CH3NH3 PbI3 film, which results in a sizeable reduction in the number of the photo-generated electrons in the (CH3NH3 PbI3 film and therefore reduces the Jsc and FF. Figure 7 shows the IPCE spectra of the ITO/CuInS2(2)/Al2O3/(CH3NH3)PbI3/Ag solar cell.
If herd effect could reduce the spread of rotavirus transmission to this age group, it has the potential to produce a sizeable reduction in the number of rotavirus cases in the elderly population in Germany.
A rehabilitation service to prevent falls in the community for older people (>60 years) was associated with a sizeable reduction in the rate of falls (55%) over the subsequent year.
It is worth to mention that in the current study we have observed a sizeable reduction in the o7 endosperm of the transcription level of O2 and VSF1 (vascular specificity factor 1), another bZIP transcriptional activator, identified in tomato and involved in vascular development [ 51, 52].
We have demonstrated that the majority of patients have a sizeable reduction in SUVmax from a single cycle of NAC with a mean change of −32.3%.
Given the assumption of no cross-resistance, a sizeable reduction in transmission occurs when Drug 2 is introduced in a population with a high prevalence of resistance to Drug 1.
For instance, let us consider a reform in the welfare state so that the indivisible cost (mu ) of education faced by individuals experiences a sizeable reduction.
Only one of the eight possible three-locus genotypes results in a sizeable reduction in fitness.
More suggestions(14)
a remarkable reduction of
a notable reduction of
a great reduction of
a broad reduction of
a large reduction of
a tremendous reduction of
a major reduction of
a valuable reduction of
a noteworthy reduction of
a vast reduction of
a big reduction of
a substantial reduction of
a considerable reduction of
a significant reduction of
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com