Horton was unsure whether banning the use of glitter in Christmas crafts would make a sizeable impact on the burden of plastic debris in the oceans, which Sir David Attenborough recently described as one of the greatest environmental scourges to befall the planet.
Few would deny that this new configuration has had a sizeable impact on public and political life in the past 30 years.
To establish appropriate Markov states it is thus necessary to estimate which variables have a sizeable impact on the costs associated with being in a state together with the transition probabilities determining movements between states.
In any case, these processes seem to have a sizeable impact on the resolution of short internal branches of the mammalian tree and phylogenetic reconstruction in general.
In contrast, amphotericin B formulations and echinocandins are only available in parenteral formulation and, thus, their administration in a prophylactic manner would be expected to have a sizeable impact on quality of life.
So if just a small proportion of Mr. Gephardt's potential labor support materializes, it could have a sizeable impact.
"I don't think it explains the big slowdown in trade you're seeing today, but if you project out 10 years, it could have a sizeable impact," said Lund.
If there's one thing she can't stand, it's anyone who demonises women, an outlook that has had a sizeable impact on her own career.
Past exposures from incinerators were likely to cause a sizeable health impact, especially for cancer, in Italy and England.
To sum it all up, the basic genesis was that I had a digital background, and I was looking for something that would make a sizeable social impact, which happened to be in education.
