However, a sizeable fraction of patients are at high risk for postoperative mortality and may refuse surgery or cannot undergo surgery due to comorbidity [ 4].
A sizeable fraction of AMPARs were present at the surface of synaptosomes and co-fractionated with NMDARs and PSD-95, indicating they were localized to synapses.
A second explanation of our findings is that a sizeable fraction of drug-resistant HIV is being transmitted by treatment-naïve persons who themselves acquired TDR.
Multiallelic CNVs (greater than 2 possible haploid copy number [ Conrad et al. 2010]) constitute a sizeable fraction of large CNVs, are highly enriched with gene content, and are closely associated with segmental duplications by virtue of their prevalent duplicated alleles (Redon et al. 2006; Conrad et al. 2010).
Anti-PDL1 and anti-PD-1 clinical trials have shown promising effects in melanoma, renal, colorectal, and non-small cell lung cancer patients, and, for the first time ever in the development of immune therapy, a sizeable fraction of patients were observed who had a durable response that increased their life span.
And secondly, because of this, there's a lot less damage to the carcass: with stun-pronging you can expect 10% carcass damage, with gas stunning it's less than 1%." Gas stunning costs on average £1 a pig more than pronging, and when you consider the price for processing a pig at their abattoir is £18.50, it is a sizeable fraction of the cost.
»Cancer cure is unlikely to occur if the rare cancer SCs are not targeted.« A number of recent reports suggest that a sizeable fraction of cancer SCs are quiescent (Ishikawa et al, 2007; Viale et al, 2009), implying that cell-cycle restriction, like in the wild-type SCs, might serve in cancer SCs to prevent self-renewal exhaustion.
Our initial assessment of three independent sets of patient tumors resistant to BRAFi suggests that the RNF125/JAK1 regulatory axis described here is relevant to a sizeable fraction of these tumors, which is a prediction that should be confirmed using larger cohorts.
For example, one of our observations is that, according to many commonly used metrics, a sizeable fraction of performance can be explained by simply predicting high node degree genes often (because high node degree genes are often multifunctional).
