Exact(3)
The analysis of AID activity on a series of modified substrates has suggested that one of the causes of the lower activity of AID on 5 mC (relative to non-methylated substrate) and the lack of the activity on 5 hmC is a size restriction against the 5-substituted C imposed by the enzyme's catalytic pocket37, 39.
Since there seems to be a size restriction of the intercalating unit, the contribution of the proline residues in the IHF arms was further investigated with respect to the proline ring conformation.
In addition to RGB thresholds, we also set a size restriction threshold for the assessment of 4G8, which excluded the measurement of immunoreactive signals with an area below 100 μm; this was necessary to ensure that physiological APP that is stained with 4G8 antibody was not included, and did not contribute to false positive values.
Similar(57)
According to the majority opinion, the Board's attention to costs and consumer choice in crafting an indirect method of regulation -- a portion size restriction rather than an outright ban -- represented unconstitutional policymaking.
We expected that a pore size restriction (8.0 μm vs. 1.0 μm) might help restrict migration of lymphocytes across these barriers and can produce a more accurate measurement of lymphocyte adhesion to the brain endothelial, gliovascular and neurovascular barriers.
Such a genome size restriction could, for instance, stem from a tight constraint on the surface to volume ratio of free-living prokaryotes, due to their need to directly extract energy and food from their surrounding environment.
This suggests that a stringent size restriction determines nuclear pore entry.
In fact, "Dao" could not have qualified before last year, since a strict size restriction (3 meters, or about 10 feet, by 3 meters by 3 meters) was in force until then.
Group interactions are reported with a cluster size restriction of 5 voxels at P < 0.001, masked with the appropriate main effect.
Thus, with ODEs it is well known that stiffness leads to a step size restriction when using explicit methods and many classes of efficient implicit methods have been designed [ 30].
Main effects and interaction effects were analyzed with one-way ANOVA implemented in SPM2 and are reported with a cluster size restriction of 10 voxels at P < 0.05 corrected for multiple comparisons according to the Family Wise Error method (Tiffany & Drobes 1991; Nichols & Hayasaka 2003).
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