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A very dissimilar example proved to be the ten short sequences included in cluster B. These proteins, which show homology with the β-domains of Int/Inv family members, range in size from 417 to 497 amino acids and lack a sizable passenger domain.
Representatives shown in Figure 3 include PITG_06480, which lacks a sizable predicted extracellular domain, and PITG_20769 which contains a 364 amino acid extracellular domain.
In conjunction with our earlier study, our data raise the possibility that chimeras result not only in altered cellular localizations due to a sizable enrichment in transmembrane domains (Frenkel-Morgenstern et al., submitted for publication), but also in the acquisition of a number of other new functions.
In sum, they got permission to tear down a sizable chunk of Brooklyn real estate and take it over via eminent domain because they promised to deliver some benefits to the city.
That's a sizable victory.
Eaton opened a sizable advantage Wednesday.
"It definitely had a sizable effect".
That's a sizable dating pool.
There is also a sizable Russian population.
There is a sizable Turkish-speaking minority.
You also need a sizable budget.
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