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The phrase "a singular strain of" is correct and usable in written English.
It is typically used to describe something unique or rare within a larger group or category. Example: The composer's latest symphony is a singular strain of brilliance that stands out among his other works.
Exact(1)
Fusing all the elements of his life story and its complicated context, a singular strain of driving, rock-country songs about heavy drinking, one-night stands, life on the road and the pressures of being the son of an icon became his stock in trade.
Similar(58)
(Ledare, for the record, is a charming, well-balanced individual, and the book does work, in an albeit disturbing way, as a fractured chronicle of a thankfully singular strain family dysfunction).
It is important to study common biological properties of transmissible viruses rather than genetic changes in a singular virus strain, to generalize the mechanisms leading to increased transmission.
Homeland security should be all about stopping very specific threats born of a virulent strain of a singular religion.
But in a constant attempt to prove that politics doesn't have to be boring, the show has also developed a singular and utterly unforgivable strain of banter – no, anti-banter.
It was a singular act of courage.
"You showed a singular lack of restraint.
It became a singular test of character.
It was a singular act of gracelessness.
The wage gap is a singular question of fairness.
All three constitute a singular act of witness.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com