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The phrase "a single thing about" is correct and usable in written English.
It can be used when emphasizing the lack of knowledge or information regarding a specific topic or subject.
Example: "I don't know a single thing about quantum physics, so I can't help you with that."
Alternatives: "anything at all about" or "one thing regarding".
Exact(44)
And there's not a single thing about it that's hip.
He did not qualify a single thing about himself.
Without changing a single thing about his platform, Cain will magically become viable.
They were basically told we're not telling you a single thing about these transactions".
To be honest, I can't remember a single thing about the contents of this book.
There isn't a single thing about his appearance or demeanour that could be mistaken for trendy.
Similar(16)
We didn't agree about a single thing: not about the merits of Paul Wolfowitz, not about the bad character of Bill Clinton, not about the writing of Evelyn Waugh, or about whether Catholicism was basically sentimental.
"Sometimes you lie in bed and you don't have a single thing to worry about," Charlie Brown reflected once.
"And when people hear that, they never want to know a single thing more about Heloise's business," Laura Lippman writes, "which is exactly as she planned it".
I really don't regret a single thing now about leaving Sheffield United because I've had so many experiences since.
"He may have left some footprints on the beaches of North Carolina, but you couldn't find any on the floor of the Senate," said Senator Mitch McConnell of Kentucky, the No. 2 Republican, who said he could not "think of a single thing" memorable about Mr. Edwards's Senate service.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com