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Furthermore, RMCE requires only a single targeting of ESC clones with the acceptor cassette, in general a slow and laborious process.
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Bosco directed a number of AOL acquisitions, including Quigo, Tacoda, Buy.at and Third Screen Media and drove development of a single targeting suite for AOL's Platform-A products.
Static images with a single target of different sizes were employed for the method performance test to evaluate the precision of the target centroid positioning, which is essential for the accuracy of the target tracking system.
An Internet provider was supposed to be providing access to the e-mail of a single target of that investigation, but the F.B.I. soon realized that the filtering controls used by the company "were improperly set and appeared to be collecting data on the entire e-mail domain" used by the individual, according to the report.
Therefore inhibiting a single target of such a network might not lead to the desired therapeutic effect.
With the advent of the Human Genome Project came the industrialisation of the drug discovery process and a belief that combinatorial chemistry and high throughput screening would deliver molecules with increased potency, against a single target of interest.
In addition this connectivity leads to more robust systems that cannot be interfered by the inhibition of a single target of that network and consequently might not lead to the desired therapeutic effect [2].
Data for HbA1c were aggregated to practice level and only referred to the achievement of a single target of ≤7.5%.
For all imprinted genes that influence a single phenotype (that is, a single target of selection), regardless of how these genes influence the trait, the parental origin of expression should be the same within a sex.
Whether or not there is a single target of selection on floral-display size, be it the inflorescence, total plant, or some combination of multiple measures of floral-display size is still unknown in Asclepias[ 21].
[7] Still, this corresponds roughly to leaving out a single target out of 14 in the NNRTI set (+/− 10% of target variation).
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