Today, there is a rather greater emphasis on developing drugs that eradicate these infectious organisms with a single, one-time dose than there is on experiments that focus on the basic science of the disease.
Based on the state and local tax codes, we determine that we need to pay two expenses: a single one-time registration tax based on the value of the car and a recurring yearly fee to get our license tabs.
On the revenue side, Mr. Gulotta apparently proposed not a single one-time source of revenue, like selling county land or property.
This study also adds to the body of literature showing that a single one-time intervention may only have a minimal effect and that on-going reinforcement is the key to maintaining HH compliance.
But connected devices are not cans of beans or sweaters, and device makers do not need to limit their products to a single, one-time purchase event more commonly associated by perishable items.
App Previews are short videos that devs can use to show their software in action, which occupy the first slot in the screenshot section of an app description, and Bundles are collections of apps that can be offered at a discounted price as a single, one-time purchase.
Spells come in several varieties: "sorceries" and "instants" have a single, one-time effect before they go to the "graveyard" (discard pile); "enchantments" and "artifacts" are "permanents" that remain in play after being cast to provide a lasting magical effect; "creature" spells (also a type of permanent) summon creatures that can attack and damage an opponent.
The epidemic curve of the first 42 cases corresponded to a single, one-time exposure.
This observation suggests that consideration of the pattern of change in hepatic insulin sensitivity over time may be more informative than a single one-time measurement.
CUPID2 is a randomized, double-blind, placebo-controlled, multinational trial evaluating a single, one-time, intracoronary infusion of the AAV1/SERCA2a vector vs. placebo added to a maximal, optimized HF drug and device regimen (NCT01643330).
Unless the intervention is a single, one-time-only dosed treatment, such as a vaccine, either dose or other "quasi-dose" aspects of how the intervention is administered may vary at least slightly between the individuals receiving the intervention in Model 1 and those receiving the intervention in Model 2.
