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The phrase "a single exception to" is correct and usable in written English.
It can be used when referring to one specific case that does not follow a general rule or pattern.
Example: "All employees must clock in by 9 AM, with a single exception to this rule for those with prior arrangements."
Alternatives: "one exception to" or "an isolated exception to".
Exact(4)
In fact, I can't think of a single exception to this rule: every attack on IS-LM I've ever seen (as opposed to suggestions that we should also look at more complex models) was followed by some kind of empirical or logical howler.
The final rounds of these events including baseball's World Series, American football's Super Bowl and the Final Four of college basketball are invariably the highlights of the United States' athletic calendar.There is a single exception to this rule: American football at the collegiate level.
During the period of treatment, and diagnosis, a single exception to DSM-IV ADHD diagnostic criteria was made regarding age of onset (nominally 7 years), for several reasons.
However, the true excess of Vα14 in the core cells was striking since the weak signal of Vα14 from lymph nodes proved, on cloning and sequencing, to be due, with a single exception, to the amplification of Vα11 which is closely related to Vα14.
Similar(53)
In a review of Now! Christmas 4, John Lucas of The Georgia Straight described the song as a "filthy electro banger" and "so blatantly about [sex] that you have to wonder how in the hell it got past the usually vigilant Now! gatekeepers", calling it the "single exception" to an otherwise bland album.
With a single exception due to a HCW's refusal to be hospitalised, SEBOV did not invade the community at large.
The single exception to this was the gsv1,2,5 cell line, which had a doubling time of 59 hours.
The single exception to this regime will be in cases involving unconvicted terror suspects who have been released.
Yet a newspaper article from the mid-fifties, headlined "TV's New Policy for Negroes," depicts Sidney as the "single exception" to the exclusion of black dramatic actors.
The single exception to this among living primates is the tarsier, in which the fibula becomes fused to the tibia.
The single exception to this is found in Genesis 19.2, where hinneh-nāʾ appears in a volitive clause.
More suggestions(15)
a one time exception to
a striking exception to
a titanic exception to
a sharp exception to
a bright exception to
a sweeping exception to
a stylistic exception to
a formal exception to
a recent exception to
a major exception to
a big exception to
a refreshing exception to
a ministerial exception to
a glorious exception to
a rare exception to
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com