Although the sequential use of SPN enhancement and FDG-PET has been shown to be potentially cost-effective, the availability of PET-CT means that both techniques could be used in a single examination with development of combined uptake/enhancement criteria.
Frequently it may not be possible to predict which single imaging marker is the best choice for any particular tumour /therapy combination and therefore the use of multiple imaging response markers in a single examination increases the probability of demonstrating response.
One girl had three examinations, seven girls had two examinations each, and 27 girls had a single examination each, for a total of 44 examinations of 35 girls.
One boy had four examinations, four boys had two examinations each, and 32 boys had a single examination each, for a total of 44 examinations of 37 boys.
We compared self-reported data at four different times over 9 years with measured values from a single examination conducted an average of 9 years after recruitment.
Extending the applications for contrast media in PET-CT to include CT perfusion imaging can allow anatomical information about tumours to be co-registered with perfusion data and metabolic information, such as glucose metabolism, in a single examination and the feasibility of this approach has recently been confirmed for head and neck cancers.
However geographical separation, coupled with the practicalities of a single examination at a single point in time, means that none of A, B, C and D ever examines with any of E, F, G and H.
Recently introduced PET/MR systems include new technologic features that allow acquisition of MRI and PET data in the same patient during a single examination providing high-quality fusion of MRI and PET images [ 5– 16].
It is a formal document, medicolegally important, committing the radiologist to an official interpretation of a single examination or procedure [2].
The combination of CT angiography together with a measurement of myocardial perfusion using a PET tracer such as 82Rb-rubidium or 13N-ammonia could, in a single examination, assess both the integrity of the cardiac arteries and the metabolic consequences for the myocardium [32].
