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The phrase "a single course of" is correct and usable in written English.
It can be used when referring to one specific instance of a course, often in the context of education or a meal.
Example: "After completing a single course of the program, students will receive a certificate of achievement."
Alternatives: "one course of" or "a solitary course of".
Exact(59)
A single course of chemo meds, imported from Belgium, costs us three million tomans – more than £600.
In fact, her world has irreversibly tilted and her mind is now set on a single course of action.
When the disease is caught early enough, it can be cured in most cases with a single course of antibiotics.
Drugs for advanced prostate cancer are typically expensive, costing tens of thousands of dollars for a single course of treatment.
A single course of treatment can be tens of thousands of pounds but what's that compared to a liver transplant and the associated costs?
Fungus medications can cost up to several hundred dollars for a single course of treatment, and many health insurers do not cover them.
One of the more striking results from the sequencing of my microbiome was the impact of a single course of antibiotics on my gut community.
Back then, a single course of ART cost around $10,000 £7,5000) a year – an unaffordable amount for poor people living in developing countries, where drugs were not provided through the public health system.
All patients received prophylactic antibiotics and a single course of antenatal betamethasone.
We examined the hypothesis that a single course of antenatal betamethasone influences the maternal fetal insulin-IGF-GH axis.
But 20-year-old Wang couldn't bring himself to commit 8 years to a single course of study.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com