A simultaneous adjustment between age and each covariate generally resulted in small changes in the age effect.
This finding persisted despite a simultaneous adjustment for migration background.
Each unhealthy lifestyle factor was significantly associated with risk of type 2 diabetes after simultaneous adjustment in the multivariate adjusted model (supplementary table A).
Simultaneous adjustments in both Andean and Yungas montane taxa suggest that vegetation dynamics in the two environments are linked to a common climatic driver.
In our study, simultaneous adjustment of wear in three planes deliberately introduced a systematic error for 2D wear estimates.
The alternative is an extremely cumbersome optimization process involving the simultaneous adjustment of an unreasonably large number of parameters.
The sample sizes used allowed us to correct for the most important factors in multi-variable models but did not permit simultaneous adjustment for all potential confounders particularly in the analysis of collaterals, where the overall number of collaterals was low.
This is the first study with substantial numbers of site-specific cancers, in which it has been possible to examine the effects of separate and simultaneous adjustment for a range of potential confounding and intermediary factors.
The associated RRs for breast cancer were 0.70 (0.49–1.01) adjusted for age and region only, and 0.75 (0.53–1.08) after simultaneous adjustment for all the factors listed in Table 3.
Multiple imputation of missing data allowed for simultaneous adjustment for several early-life factors in log-binomial regression models without reductions in sample size.
Because none of these three SNPs maintained a statistically significant association with eGFR in multivariate models with simultaneous adjustment for the other two variants, we argue that these variants may reflect the presence of one common genetic source of phenotypic variation (Fig. 2).
