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Data from 5 to 10 time courses were averaged and fitted to a double-exponential function using the simplex procedure of the Biokine software (Bio-logic).

Data from six to eight time-courses obtained in the different conditions were averaged and fitted to a mono-exponential function using the simplex procedure of the Biokine software (Bio-logic).

The GANLS three step approach (Coan 2011) first employs a genetic algorithm to search global parameter space, a simplex algorithm to search local parameters space, and finally a bootstrapping procedure to derive the uncertainty associated with the parameter estimates.

The parameters of both models were obtained independently through a Simplex optimization procedure ('Materials and methods').

The increase in signal intensity was, on the average, 3.9 times for the isotopes considered for the simplex procedure.

For simplicial algorithms, one frequently finds a complete labeled sub-simplex (full labeled sub-simplex) in a simplex to approximate a fixed point.

Also several modifications to the simplex procedures are reviewed.

Starting from a carefully designed feature-sensitive triangulation, we apply the so-call link triangulation procedure to obtain a feature-sensitive configuration family and then construct simplex spline bases as well as spline surface on it.

An automated procedure, based on a simplex algorithm, was used to optimize the 35 sets of metal-dependent structural parameters for each metal ion.

Weiss [17] proposed a simplex-like algorithm to solve the separated continuous-time linear programming problem.

Then, a simplex method is used to perform the optimization with initial value in.