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The phrase "a simple assumption that" is correct and usable in written English.
It can be used when introducing a basic or straightforward belief or premise that is taken for granted in a discussion or argument.
Example: "In our analysis, we start with a simple assumption that all participants have equal access to resources."
Alternatives: "a basic premise that" or "a straightforward belief that".
Exact(15)
At its core is a simple assumption: that the best way to learn to perceive the biosphere is to pay close attention to our immediate surroundings.
Behind the change in thinking lies a simple assumption: that as IT's potency and ubiquity have increased, so too has its strategic value.
A simple assumption that equation (8) has a positive real root ({omega_{0}}) is ({C_{3}} < 0).
The estimation is obtained based on a simple assumption that each nonisomorphic graph is generated with an equal probability.
They interpreted the anomaly as an evidence of coseismic frictional heat based on a simple assumption that broadening of the anomaly is proportional to the thermal diffusion length.
The reason for this choice follows from a simple assumption that all similarity measures express the true (unknown) similarities with some errors (biases and random errors, as well), so using the average, these errors are cancelled out at least partially.
Similar(45)
There are enough crosscurrents to discourage any simple assumption that demographic change guarantees Republican continuity in the White House.
Here we show, under some very simple assumptions, that when testing for differences between two samples for a given expression level, a longer gene will be more significant that a shorter gene.
On the other hand, plenty of scope for creativity exists with the Black-Scholes method, even given the few simple assumptions that are used.
In our 1-D inversion of subsurface resistivity structure, the largest uncertainties in the model arise due to the simple assumptions that must be made.
A simple assumption would be that herbivores maximize their energy intake by selecting the most nutritious food items available within their home range.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com