Sentence examples for a similar active from inspiring English sources
A similar active silence surrounds his work.
This led to the exploration of conformationally restricted cyclic scaffolds bearing a similar active conformation.
A similar active ingredient, arsenic stone, has long been used in China and elsewhere to treat fevers, depression and arthritis.
Highly conserved mechanistically important residues in the PNP synthase family imply a similar active site organization and reaction mechanism for all family members.
Humans can express multiple forms of neuraminidase enzymes (NEU1, NEU2, NEU3, NEU4) that share a similar active site and enzymatic mechanism with their viral counterparts.
It is possible that the inhibitory effect of Reactive Blue 2 on APE1 occurs via a similar active site occupancy mechanism [49], consistent with the recent report that free nucleotides (e.g. ATP) can regulate APE1 endonuclease efficiency [28].
The scores for the frame pairs are summed up to get an overall score for all conserved regions, whereas a higher score should indicate a more similar active center and more similar binding properties.
PP2 and SI-1 are known also to inhibit the kinase activity Receptor Interacting Protein 2 (RIP2), which shares a very similar active site (Bain et al., 2007).
In summary, we could demonstrate that chlorite dismutases from both main lineages have, despite significantly different overall structures, a very similar active site and access channel architecture and as a consequence redox chemistry.
The only structural data available for these enzymes are those derived from molecular modeling studies of mouse SMO [ 5, 10, 11] and mouse APAO [ 12] which indicated a very similar active site environment for the two proteins, making it difficult to rationalize their different substrate specificity and sensitivity to small molecule inhibitors [ 13].
Biologic drugs are developed from human and animal proteins instead of through a chemical process, and there is no way to make a generic with similar active ingredients when the "active ingredients" in biologic medications are living cells.
